Lakshmi's present treatment is Blood Transfusion every two weeks and she is under treatment with Desferrioxamine Injection IP (Desferal* 0.5g) 3 vials per day, 6days per week.
She has been consulted by two different doctors' opinions; both were of the same response to get done at the earliest the Hip replacement surgery given a time of maximum 30 days by the doctors. Currently, she is being treated at Private Hospital, Bangalore.
Further, the cost of operation was said by doctors to be Rupees 4,00,000 and hence approach with this kind request message for possible support.
Hence, being left without any solutions approaching your good selves to kindly spare some time to read this message and appreciate your generosity donations to help Lakshmi have a quality life.
I would like to share a brief info and complications regarding the said Major Thalassemia as follows:
Thalassemia is an inherited blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued.
This form of thalassemia is usually so severe that it requires regular blood transfusions.
Thalassemia signs and symptoms can include:
A poor appetite
Failure to thrive
Pale or yellowish skin
In cases of severe/Major thalassemia, the following complications occur:
Iron overload. People with thalassemia can get too much iron in their bodies, either from the disease or from frequent blood transfusions. Too much iron can result in damage to your heart, liver, and endocrine system, which includes hormone-producing glands that regulate processes throughout your body.
Infection. People with thalassemia have an increased risk of infection.
Bone deformities. Thalassemia can make your bone marrow expand, which causes your bones to widen. This can result in abnormal bone structure, especially in your face and skull. Bone marrow expansion also makes bones thin and brittle, increasing the chance of broken bones.
Enlarged spleen. The spleen helps your body fight infection and filter unwanted material, such as old or damaged blood cells. Thalassemia is often accompanied by the destruction of a large number of red blood cells. This causes your spleen to enlarge and work harder than normal.
An enlarged spleen can make anemia worse, and it can reduce the life of transfused red blood cells. If your spleen grows too big, your doctor might suggest surgery to remove it.
Slowed growth rates. Anemia can both slow a child's growth and delay puberty.
Heart problems. Congestive heart failure and abnormal heart rhythms can be associated with severe thalassemia.
For moderate to severe thalassemia, treatments include:
Frequent blood transfusions. More severe forms of thalassemia often require frequent blood transfusions, possibly every few weeks. Over time, blood transfusions cause a buildup of iron in your blood, which can damage your heart, liver, and other organs.
Chelation therapy. This is treatment to remove excess iron from your blood. Iron can build up because of regular transfusions. Some people with thalassemia who don't have regular transfusions can also develop excess iron. Removing the excess iron is vital for your health.
To help rid your body of the extra iron, you might need to take an oral medication, such as deferasirox (Exjade, Jadenu) or deferiprone (Ferriprox). Another drug, deferoxamine (Desferal), is given by needle.
Stem cell transplant. Also called a bone marrow transplant, a stem cell transplant might be an option in some cases. For children with severe thalassemia, it can eliminate the need for lifelong blood transfusions and drugs to control iron overload.
This procedure involves receiving infusions of stem cells from a compatible donor, usually a sibling.