Autism Spectrum Disorder (ASD) is a congenital condition with a spectrum of expression. It is prevalent in 1:68 male live births with a varied expression, from mild to severe. Recent research indicates that the intestinal bacteria flora have a role in modifying human behavior. So it is ex,pected that, the bacteria flora may have a connection with the severity in ASD. If a bacterial biomarker(s) can be identified, it may be helpful in the management of ASD in future, as probiotic intervention. We are trying to identify such marker from the oral and stool microbiota. For initial experiment and identification of bacteria by 16s RNA method, we need funding. If we can get some preliminary result, we can apply for funding to ICMR/CSIR/DST/DBT. For initial experiment (twin study), we need Rs. 2,50, 000/-. We have managed Rs. 37,000/- from our savings. Please donate small amount, if possible, for carrying out this research. Any scientific suggestion is also welcome. We are also interested in joint research programme.